Dead Sea and the new research in the field of psoriasis

Research Center of the Dead Sea and Arava
Under the auspices of the University. Ben-Gurion University of the Negev

The Dead Sea has a more favorable and more lasting impact in the treatment of psoriasis

The percentage of patients who a month later, the index reached PASI 75 and remission time after climatotherapy Dead Sea

Published in the International Journal of Dermatology
(Int J Dermatol 2007, 46, 1087 - 1091)

Summary:
Research Center of the Dead Sea and Arava more than ten years, participated in the study and assessment of therapeutic efficacy of the natural resources of the Dead Sea in the treatment of chronic diseases. Studied in detail psoriasis, treatment which is often the most efficient compared to the treatment of other skin diseases.

Once in the previously published studies had established the optimal duration of climatotherapy (finding the sun), its relative effect on thalassotherapy (immersion in sea water), the nature of the mechanism of action at the cellular and immunological level, as well as after it was revealed the absence of skin carcinogenesis prolonged exposure to the sun at the Dead Sea, as part of the study was conducted the first follow-up care for patients with psoriasis in their home country for twelve months.

As the survey data, the treatment was highly effective and had no side effects, the duration of therapeutic effect in the first year after treatment in case of re-emergence of large ulcers accounted for more than six months.

Cost weeks of remission achieved by the climate-Dead Sea is lower than for other modes of treatment, for which the assessment is made in another study. Some of these regimes (immunosuppressive treatment and PUVA therapy) may be accompanied by serious side effects, while others, such as the recently introduced biological drugs, too expensive.

The percentage of patients who after one month PASI index was 75,
and time of remission after climatotherapy at the Dead Sea

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This document is a summary of research on the effectiveness and duration of clinical remission in patients with psoriasis blyashechnym held course climatotherapy the Dead Sea. The study was conducted in collaboration with the Israeli doctors from the Dead Sea and the German doctors practicing in the state of Saxony.

The study covered 64 patients with psoriasis, who arrived in Israel from Germany and held at the Dead Sea 28-day course of Climatology treatment, which included a daily exposure to the sun in the morning and afternoon. Time sun exposure was calculated on the basis of individual parameters and based on the measurement of ambient solar radiation. Thalassotherapy included a gradual increase in the duration of immersion of the Dead Sea.

On arrival and before departure of the patients undergo an assessment by index PASI (indicator area of the skin lesion and its severity in psoriasis) and follow-up inspections in the twelve months in Germany with the message of the appearance of recurrent ulcers on the skin. Then periodically evaluated in terms of PASI.

Rating:
Time of recurrence of skin lesions after a complete or almost complete clearance at the end of climatotherapy defined as the duration of remission.

Time elapsed before the 50-percent relapse of the initial level of PASI, accepted as the duration of therapeutic effect.

Results:
Effect climatotherapy: PASI index decreased from an average of 31.7 (this was before treatment) to 1.4 at the end of the course climate-that is, there is an improvement of 95%.

The average duration of remission was 23.1 weeks, the average duration of therapeutic effect - 33.6 weeks.

Statistical multivariate analysis showed that more prolonged phase of remission was observed in younger patients.

This study suggests that the four-week course climatotherapy Dead Sea is effective in treating patients with psoriasis blyashechnym. The results indicate a preference for this method compared with other modes of treatment: almost non-existent side effects, patients receiving treatment in an atmosphere of holiday, communicating with other vacationers, as other studies show, contributes to improving the quality of their lives.